| 1991 | The opening of the college with Sr Judith Sippel as Foundation Principal |
| 1995 | Mary MacKillop Catholic College celebrates the Beatification of Mary MacKillop |
| 2009 | Year of renewal; Mary MacKillop Catholic College celebrates the beginning of the building of a chapel, drama studio, dance studio, the new science laboratories, library and hospitality rooms |
| 2010 | Mary MacKillop Catholic College celebrates the Canonisation of Saint Mary of the Cross MacKillop on the 17th of October and the commissioning of a statue of Mother Mary for the college |
| 2011 | Opening and blessing of the new buildings: chapel, drama studio, dance studio, the new science laboratories, library and hospitality rooms |
| 2012 | Unveiling and blessing of St Mary of the Cross MacKillop’s statue |
| 2016 | Celebration of 25 years of Mary MacKillop Catholic College |
| 1991 – 2002 | Sr Judith Sippel |
| 2002 – 2002 | Mrs Jennifer Stirling |
| 2003 – 2007 | Ms Robyn Glover |
| 2008 – 2008 | Ms Jennifer Rickard |
| 2009 – 2017 | Mrs Narelle Archer |
| 2018 – | Ms Gilda Pussich |
| 1991 – 1995 | Not appointed – SRC Committee only |
| 1996 | Lorella Sitta |
| 1997 | Brenda Lui |
| 1998 | Shameela Karunakaran |
| 1999 | Ramina Omran |
| 2000 | Amanda Jo Feeney |
| 2001 | Cecilia Phu |
| 2002 | Diana Gumieniuk |
| 2003 | Elizabeth Laria |
| 2004 | Rochelle Brunet |
| 2005 | Monica Liska |
| 2006 | Jacqueline Loprete |
| 2007 | Debbie Tran |
| 2008 | Tanya Miocic |
| 2009 | Stephanie Michalef |
| 2010 | Tanika Kehlet |
| 2011 | Jessica Nissan |
| 2012 | Brenda Alvarez |
| 2013 | Samantha Hemmings |
| 2014 | Amanda Robertson |
| 2015 | Tiana Balgos |
| 2016 | Tylah Fragiadakis |
| 2017 | Katarina Ferkula-Cohen |
| 2018 | Erin Zappia |
| 2019 | Jassamyn Reyes-Vega |
| 2020 | Summer Rosewall |
| 1991 | — |
| 1992 | Ann Duong |
| 1993 | Vivian Mousholof |
| 1994 | Margaret Kha |
| 1995 | Thao Nguyen |
| 1996 | Ann Warda |
| 1997 | Dao Nguyen |
| 1998 | Shameela Karunakaran |
| 1999 | Karen Lang |
| 2000 | Stephanie Helpher |
| 2001 | Dawnie Lam |
| 2002 | Phuong Trinh |
| 2003 | Jamie Kulczycki |
| 2004 | Sara Bontempo |
| 2005 | Alana Baldi |
| 2006 | Frances Aziz |
| 2007 | Sandra Yousheyah |
| 2008 | Natali Shlaimon |
| 2009 | Anna-Marie Tolic |
| 2010 | Maree La Delfa |
| 2011 | Tiffany Tu |
| 2012 | Judy Do |
| 2013 | Yasameen Al Khafaji |
| 2014 | Rozella Chum |
| 2015 | Erin Tang |
| 2016 | Nancy Cece |
| 2017 | Olivia Chum & Chloe Krtovski |
| 2018 | Dana Odish |
| 2019 | Sarah Dzung Pham |
| 2020 | — |
| 1991 | Joanne Briffa |
| 1992 | Theresa Duong |
| 1993 | Jenny Delgado |
| 1994 | Jacqueline Stuban |
| 1995 | Rachael McShane |
| 1996 | Barbara Jesionkowski |
| 1997 | Brenda Lui |
| 1998 | Nicole Kealy |
| 1999 | Rebecca Fasan |
| 2000 | Renee Elvy |
| 2001 | Cecilia Phu |
| 2002 | Thuy Huynh |
| 2003 | Loren Zarb |
| 2004 | Kylie Lapierre |
| 2005 | Phuong Nguyen |
| 2006 | Emily Grant |
| 2007 | Nour George |
| 2008 | Grace La Delfa |
| 2009 | Taylah-Rae Brunetta |
| 2010 | Julina Yako |
| 2011 | Brittany Ross |
| 2012 | Merna Nino |
| 2013 | Diana Rojas Ruiz |
| 2014 | Angela Nguyen |
| 2015 | Isabella Casella |
| 2016 | Mary Toma |
| 2017 | Mariam Polis |
| 2018 | Maria Ruiz Davila |
| 2019 | Liana Keo |
| 2020 | — |